Daniil Medvedev became the highest seed to fall in the French Open singles after losing to Australia’s Alex de Minaur in the men’s fourth round.
Russian fifth seed Medvedev, 28, was beaten 4-6 6-2 6-1 6-3 at Roland Garros.
Medvedev needed treatment for blisters on his feet in the second set and lost nine of the next 10 games when he returned from a medical timeout.
The former world number one, who has never gone past the French Open quarter-finals, improved in the fourth set after going off court again.
De Minaur is the first Australian man to reach the Roland Garros quarter-finals since Lleyton Hewitt in 2004.